ABOUT THE LAB

Our lab uses and develops both computational and experimental tools to ask fundamental questions about microbiology. We are especially interested in how microbial communities assemble, adapt, and impact their environments and hosts.

Recent Publications

Natural Carrier-Free Self-Assembled Binary Polyphenol Nanoparticles Remodel the Gut Microenvironment for Inflammatory Bowel Disease Prevention
Developing biocompatible, multi-target therapeutics remains a critical challenge in the management of inflammatory bowel disease (IBD). …
Qiwen Xie, Huan Xu, Xiaoming Yang, Ying Chen, Zhenjiang Zech Xu
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Porphyromonas Gingivalis Induces Intestinal Inflammation through Gingipain-Dependent Gut Microbiome Dysbiosis
Background Porphyromonas gingivalis (Pg), a key pathogen in periodontitis, is implicated in various systemic diseases such as …
Ming Li, Jiyun Cui, Ru Qu, Rulong Liu, Yifan Sun, Ping Li, Juan Liu, Adrian Low, Xiaochang Huang, Fei Gan, Zhenjiang Zech Xu
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Propylparaben Induces Immunotoxicity in Zebrafish via Oxidative Stress and Gut Microbiota-Immune Axis Dysregulation
Propylparaben (PP), a widely used preservative, has an unclear immunotoxicity profile. In this study, zebrafish embryos were exposed to …
Yong Huang, Jing Hu, Huan Xu, Runhao Zhu, Liting Liu, Xiaomei Chen, Yifan Sun, Yuwei Zhao, Yebing Zhong, Bo Cheng, Xiaochang Huang, Huiqiang Lu, Zhenjiang Zech Xu
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Scikit-Bio: A Fundamental Python Library for Biological Omic Data Analysis
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Dietary Nisin Exacerbates Diabetic Vascular Complications through Gut Microbiota Modulation and NF-κB Signaling
Diabetic vascular complications (DVCs) are a major cause of morbidity in diabetes, with gut microbiota dysbiosis emerging as an …
Liting Liu, Yong Huang, Huan Xu, Yifan Sun, Zhenjiang Zech Xu, Xiaochang Huang
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