Conserved 3′ stem-loop structures enable comprehensive analysis of bacterial transcription termination in metagenomes

Yunfan Jin, Jiyun Cui, Rulong Liu, Hongli Ma, Xiaomin Xu, Shufang Wu, Fei Gan, Zhi John Lu, 徐振江
七月 2026
引用 DOI URL

摘要

Bacterial transcription termination is a critical yet underexplored layer of gene regulation in microbial ecosystems. Existing computational tools, however, primarily focus on predicting transcript 3′ ends generated by Rho-independent terminators (RITs) in a few model species, leaving gaps in understanding those generated by Rho-dependent terminators (RDTs) and their diversity across Bacteria.

类型
期刊文章
出版物
Microbiome
Bacterial Terminator Transcription Termination Transcription Unit Prediction
Rulong Liu
Rulong Liu
M.S. student
徐振江
徐振江
Professor

My research interests include microbiome, (meta)genomics and machine learning.